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Uji Efikasi -Organ Kulit dan Lokomosi-

Persembuhan luka laserasi

Hewan : Rat, Mouse, Cavia
Modeling : Wound healing
Metode : Luka kulit sayatan
Analisa : makroskopi, histopatologi
Referensi : Journal of Visualized Experiments; doi: 10.3791/50265

No. protocol #SK/011

Persembuhan luka terbuka

Hewan : Rat, Mouse, Cavia
Modeling : Wound healing
Metode : Luka kulit puncuture
Analisa : makroskopi, histopatologi
Referensi : Journal of Visualized Experiments; doi: 10.3791/50265

No. protocol #SK/012

Persembuhan luka gangrene

Hewan : Rat, Mouse, Cavia
Modeling : Wound healing
Metode : Ischemic flap
Analisa : makroskopi, histopatologi
Referensi : Methods Mol Biol. 2013; 1037: 265–274.; doi: 10.1007/978-1-62703-505-7_15

No. protocol #SK/013

Skin whitening

Hewan : Rat, Mouse, Cavia
Modeling : Depigmenting
Metode : UV B Heat Induced
Analisa : makroskopi, histopatologi
Referensi : International journal of Molecular Science; doi: 10.3390/ijms12084819

No. protocol #SK/017

Hipersensitivitas kulit

Hewan : Rat, Mouse, Cavia
Modeling : Inflamasi
Metode : UV B Induced
Analisa : makroskopi, histopatologi
Referensi : Immunology. 1968 Sep; 15(3): 405–416; PMCID: PMC1409462

No. protocol #SK/018

Anti-inflammasi kulit

Hewan : Rat, Mouse
Modeling : Inflamasi
Metode : Induced
Analisa : makroskopi, histopatologi
Referensi : PLoS One. 2018; doi: 10.1371/journal.pone.0194667. eCollection 2018

No. protocol #SK/019

Rheumatoid arthritis

Hewan : Rat, Mouse, Cavia
Modeling : Inflamasi
Metode : CFA Induced
Analisa : makroskopi, histopatologi
Referensi : Inflammopharmacology. 2015; doi: 10.1007/s10787-015-0241-4

No. protocol #OS/020

Osteoporosis

Hewan : Rat, Mouse, Cavia
Modeling : Trauma
Metode : Surgery
Analisa : makroskopi, histopatologi
Referensi : Frontiers in Endrocrinology; doi: 10.3389/fendo.2019.00277

No. protocol #OS/025

Uji Efikasi -Organ Mata dan Telinga-

Kornea Ulser

Hewan : Rat, Mouse, Cavia
Modeling : Trauma, Iritasi
Metode : Surgery, induksi
Analisa : makroskopi, histopatologi
Referensi : PLOS ONE 10(9): e0137559. https://doi.org/10.1371/journal.pone. 0137559

No. protocol #EY/026

Iritasi

Hewan : Rat, Mouse, Cavia
Modeling : Iritasi
Metode : Induksi
Analisa : klinis, makroskopi, histopatologi
Referensi : Comparatie Medicine; PMCID: PMC5073061

No. protocol #EY/027

Blepharitis

Hewan : Rat, Mouse, Cavia
Modeling : Inflamasi
Metode : Induksi
Analisa : klinis, makroskopi, histopatologi
Referensi : Invest Ophthalmol Vis Sci. 2014; doi: 10.1167/iovs.13-13685

No. protocol #EY/028

Tracheitis

Hewan : Rat, Mouse, Cavia
Modeling : Iritasi induksi
Metode : Instilasi
Analisa : makroskopi, histopatologi
Referensi : Toxicologic Pathology; DOI: 10.1177/0192623309353423

No. protocol #RS/033

Acute Pneumonia/ARDS

Hewan : Rat, Mouse, Cavia
Modeling : Inflamasi
Metode : Instilasi Induksi
Analisa : makroskopi, histopatologi
Referensi : Journal of thoracic Diseae; doi: 10.21037/jtd.2019.04.14

No. protocol #RS/034

Lung Granuloma

Hewan : Rat, Mouse, Cavia
Modeling : Infeksi
Metode : Bakterial infeksi
Analisa : makroskopi, histopatologi
Referensi : Antimicrob Agents Chemother; doi: 10.1128/AAC.00217-12

No. protocol #RS/035

Anti-tussive

Hewan : Rat, Mouse
Modeling : Inflamasi Mast Cell
Metode : Induksi
Analisa : mucus, makroskopi, histopatologi
Referensi : Int. J. Drug Dev. & Res., 2014, 6 (4): 93-102

No. protocol #RS/036

Obstruksi pembuluh darah

Hewan : Rat, Mouse, Cavia
Modeling : Ligasi
Metode : Bedah
Analisa : makroskopi, histopatologi
Referensi : eLife; doi: 10.7554/eLife.33670

No. protocol #HR/041

Diabetic microangiopathi

Hewan : Rat, Mouse
Modeling : Induksi
Metode : Induksi
Analisa : histopatologi
Referensi : Experimental Biology and Medicine; https://doi.org/10.1177/153537020623100210

No. protocol #HR/042

Uji Efikasi -Organ Sistem Pencernaan-

Candidiasis

Hewan : Rat, Mouse, Cavia
Modeling : Infeksi jamur
Metode : Infeksi
Analisa : klinis, makroskopi, histopatologi
Referensi : Journal of Fungi; doi: 10.3390/jof4010021

No. protocol #DG/043

Wound healing gingiva

Hewan : Rat, Mouse, Cavia
Modeling : wound healing
Metode : Surgery, induksi
Analisa : klinis, makroskopi, histopatologi
Referensi : J Dent Res; doi: 10.1177/0022034514563750.

No. protocol #DG/044

Infestasi parasit

Hewan : Rat, Mouse
Modeling : Parasit
Metode : Infeksi
Analisa : klinis, makroskopi, histopatologi
Referensi : Front Immunol; doi: 10.3389/fimmu.2018.00807

No. protocol #DG/049

Gastrointestinal Cancer

Hewan : Rat, Mouse
Modeling : Cancer
Metode : Induksi
Analisa : makroskopi, histopatologi
Referensi : J Gastroenterol Hepatol; doi: 10.1111/jgh.13297

No. protocol #DG/050

Liver Cancer

Hewan : Rat, Mouse
Modeling : Cancer
Metode : Induksi
Analisa : makroskopi, histopatologi
Referensi : Journal of Hepatology; DOI:https://doi.org/10.1016/j.jhep.2020.04.011

No. protocol #DG/051

Probiotik

Hewan : Rat, Mouse
Modeling : –
Metode : Gavage tubing
Analisa : klinis, makroskopi, histopatologi, bacterial localization, harmful enzyme, organ bactaria number
Referensi : Plos One;
doi: 10.1371/journal.pone.0159851

No. protocol #DG/052

Ligasi arteri renalis

Hewan : Rat, Mouse
Modeling : Infark
Metode : Surgery
Analisa : makroskopi, histopatologi
Referensi : Trans Am Clin Climatol Assoc; PMCID: PMC2917126

No. protocol #EX/057

Renal calculi

Hewan : Rat, Mouse, Cavia
Modeling : Inflamasi
Metode : Induksi
Analisa : makroskopi, histopatologi
Referensi : World Journal of Nephrology; doi: 10.5527/wjn.v5.i2.189

No. protocol #EX/058

Hidronefrosis

Hewan : Rat, Mouse, Cavia
Modeling : Obstruksi
Metode : Surgery
Analisa : makroskopi, histopatologi
Referensi : AJP, Renal Physiology; https://doi.org/10.1152/ajprenal.00001.2016

No. protocol #EX/059

Uji Efikasi -Organ Sistem Imun-

Imunomodulator

Hewan : Rat, Mouse
Modeling : –
Metode : Gavage tubing
Analisa : klinis, hematologi, fagositosis, makroskopi, histopatologi
Referensi : Eidence Based Comp. and Altern. Medicine; https://doi.org/10.1155/2015/479412

No. protocol #IM/060

Uji Efikasi -Gangguan Metabolisme-

Diabetes Melitus

Hewan : Rat, Mouse
Modeling : Blood glucose
Metode : Induksi
Analisa : klinis, hematologi, makroskopi, histopatologi
Referensi : Journal of Diabetes Res.; doi: 10.1007/s10555-012-9405-5

No. protocol #MB/065

Obesitas

Hewan : Rat, Mouse
Modeling : Obesitas
Metode : High fat diet
Analisa : klinis, hematologi, makroskopi, histopatologi
Referensi : Nutrition and Metabolic Insight; https://doi.org/10.4137/NMI.S32907

No. protocol #MB/066

Hipercholesterol

Hewan : Rat, Mouse
Modeling : hipercholesterol
Metode : High cholesterol diet
Analisa : klinis, hematologi, makroskopi, histopatologi
Referensi : The Journal of Nutrition; https://doi.org/10.1093/jn/76.3.242

No. protocol #MB/067

Stunting

Hewan : Rat, Mouse
Modeling : Stunting
Metode : Induksi
Analisa : klinis, hematologi, makroskopi, histopatologi
Referensi : Scientific Reports volume 10, Article number: 15581

No. protocol #MB/068

Neurectomy

Hewan : Rat, Mouse
Modeling : Neurctomy
Metode : Surgery
Analisa : klinis, makroskopi, histopatologi
Referensi : Anat Cell Biol; doi: 10.5115/acb.2015.48.4.268

No. protocol #BR/073

Paralysis

Hewan : Rat, Mouse
Modeling : Paralysis
Metode : Surgery, induksi
Analisa : klinis, makroskopi, histopatologi
Referensi : EBioMedicine; doi: 10.1016/j.ebiom.2017.09.017

No. protocol #BR/074

Alzheimer

Hewan : Rat, Mouse
Modeling : Alzheimer
Metode : Induksi
Analisa : klinis, makroskopi, histopatologi
Referensi : Biomedical Research and Therapy; https://doi.org/10.15419/bmrat.v6i11.575

No. protocol #BR/075

Epilepsi

Hewan : Rat, Mouse
Modeling : Convulsif
Metode : Induksi
Analisa : klinis, makroskopi, histopatologi
Referensi : Zool Res.;
doi: 10.24272/j.issn.2095-8137.2017.042

No. protocol #BR/076

Memori

Hewan : Rat, Mouse
Modeling : –
Metode : gavage tubing
Analisa : klinis, makroskopi, histopatologi
Referensi : Life Sciences; DOI: 10.1016/j.lfs.2010.09.004

No. protocol #BR/077

Persembuhan luka bakar

Hewan : Rat, Mouse, Cavia
Modeling : Wound healing
Metode : Controlled heat induced
Analisa : makroskopi, histopatologi
Referensi : Methods Mol Biol. 2013; 1037: 265–274.; doi: 10.1007/978-1-62703-505-7_15

No. protocol #SK/014

Penuaan kulit (Kolagen)

Hewan : Rat, Mouse, Cavia
Modeling : Wound healing
Metode : Ovariectomy, induced
Analisa : makroskopi, histopatologi special staining
Referensi : Methods Mol Biol. 2013; 1037: 265–274.; doi: 10.1007/978-1-62703-505-7_15

No. protocol #SK/015

Skin fibrosis (Scars)

Hewan : Rat, Mouse, Cavia
Modeling : Scars
Metode : fibrosis induced
Analisa : makroskopi, histopatologi special staining
Referensi : Current Protocols in Immunology 126(1); DOI: 10.1002/cpim.88

No. protocol #SK/016

Osteoarthritis

Hewan : Rat, Mouse, Cavia
Modeling : Inflamasi
Metode : MIA Induced
Analisa : makroskopi, histopatologi
Referensi : PlosOne 2020; https://doi.org/10.1371/journal.pone.0239663

No. protocol #OS/021

Osteoarthritis 2

Hewan : Sheep
Modeling : Menisectomy
Metode : Surgery
Analisa : makroskopi, histopatologi
Referensi : Plos One 2020; https://doi.org/10.1371/journal.pone.0239663

No. protocol #SK/022

Persembuhan tulang rahang dan gigi

Hewan : Rat, Cavia
Modeling : Trauma
Metode : Retraksi
Analisa : makroskopi, histopatologi
Referensi : Journal of Visualized Experiments; doi: 10.3791/58186

No. protocol #OS/023

Fraktura tulang

Hewan : Rat, Mouse, Cavia
Modeling : Trauma
Metode : Surgery
Analisa : makroskopi, histopatologi
Referensi : Journal of Visualized Experiments; doi: 10.3791/58186

No. protocol #OS/024

Conjuctivitis

Hewan : Rat, Mouse, Cavia
Modeling : Wound healing
Metode : Controlled heat induced
Analisa : klinis, makroskopi, histopatologi
Referensi : journal of Immunology; doi: 10.4049/jimmunol.175.8.4897

No. protocol #EY/029

Bacterial Keratitis

Hewan : Rat, Mouse, Cavia
Modeling : Infeksi
Metode : Infeksi bakteri
Analisa : klinis, makroskopi, histopatologi
Referensi : journal of Biomedicine and Biotechnology; doi: 10.1155/2011/680642

No. protocol #EY/030

Otitis

Hewan : Rat, Mouse, Cavia
Modeling : Infeksi
Metode : Bakterial infeksi
Analisa : makroskopi, histopatologi special staining
Referensi : Plos Pathogens; https://doi.org/10.1371/journal.ppat.1007696

No. protocol #EY/031

Uji Efikasi -Organ Saluran Pernafasan-

Rhinitis-Sinusitis

Hewan : Rat, Mouse, Cavia
Modeling : Gas iritasi
Metode : Aerosol induksi
Analisa : klinis, makroskopi, histopatologi
Referensi : Laryngoscope Investig Otolaryngol; doi: 10.1002/lio2.117

No. protocol #RS/032

Asthma

Hewan : Rat, Mouse
Modeling : bronchoconstriction
Metode : Induksi
Analisa : makroskopi, histopatologi
Referensi : Journal of asthma and allergy; doi: 10.2147/JAA.S121092

No. protocol #RS/037

Uji Efikasi -Organ Sistem Sirkulasi-

Hipertensi

Hewan : Rat, Mouse
Modeling : Ligasi, ACE inhibitor
Metode : surgery, induksi
Analisa : klinis, makroskopi, histopatologi
Referensi : Amarican Journal of Physiology; https://doi.org/10.1152/ajpregu.00306.2004

No. protocol #HR/038

Infark Myocard

Hewan : Rat, Mouse, Cavia
Modeling : Ligasi
Metode : Surgery
Analisa : makroskopi, histopatologi
Referensi : Journal of Visualized Experiments. (99), e52197 (2015);
doi: 10.3791/59591

No. protocol #HR/039

Plaque Atheroma

Hewan : Rat, Mouse, Rabbit
Modeling : High Fat Diet and Chol
Metode : Diet
Analisa : makroskopi, histopatologi
Referensi : Plos One; https://doi.org/10.1371/journal.pone.0141019

No. protocol #HR/040

Diare

Hewan : Rat, Mouse, Cavia
Modeling : Hiperperistaltik
Metode : induce, infeksi
Analisa : klinis, makroskopi, histopatologi
Referensi : Genome Biology; doi: 10.1186/gb-2008-9-8-r122

No. protocol #DG/045

Irritable bowel syndrome

Hewan : Rat, Mouse
Modeling : Inflamasi
Metode : Induksi, stress
Analisa : klinis, makroskopi, histopatologi
Referensi : Journal of Clinical Medicine; doi: 10.3390/jcm7010004

No. protocol #DG/046

Colitis

Hewan : Rat, Mouse
Modeling : Inflamasi
Metode : Induksi, stress
Analisa : klinis, makroskopi, histopatologi
Referensi : Methods Mol Biol; doi: 10.1007/978-1-4939-1215-5_25.

No. protocol #DG/047

Gastritis

Hewan : Rat, Mouse
Modeling : Inflamasi
Metode : Induksi, stress
Analisa : klinis, makroskopi, histopatologi
Referensi : World J Gastroenterol; doi: 10.3748/wjg.v10.i21.3212

No. protocol #DG/048

Ulkus intestine

Hewan : Rat, Mouse, Cavia
Modeling : Ulcer
Metode : Induksi
Analisa : klinis, makroskopi, histopatologi
Referensi : Nat Protoc.; doi: 10.1038/nprot.2007.41.

No. protocol #DG/053

Liver fibrosis

Hewan : Rat, Mouse
Modeling : Cancer
Metode : Induksi
Analisa : makroskopi, histopatologi
Referensi : Journal of Hepatology; DOI:https://doi.org/10.1016/j.jhep.2020.04.011

No. protocol #DG/054

Partial hepatectomy

Hewan : Rat, Mouse
Modeling : Cancer
Metode : Induksi
Analisa : makroskopi, histopatologi
Referensi : Journal of Hepatology; DOI:https://doi.org/10.1016/j.jhep.2020.04.011

No. protocol #DG/055

Uji Efikasi -Organ Sistem Ekskresi-

Acute Nefritis

Hewan : Rat, Mouse
Modeling : Inflamasi
Metode : Induksi
Analisa : makroskopi, histopatologi
Referensi : Intl. Journal of Nephrology; https://doi.org/10.1155/2018/8424502

No. protocol #EX/056

Imunosupresi

Hewan : Rat, Mouse
Modeling : –
Metode : Induce, genetic
Analisa : klinis, hematologi, fagositosis, makroskopi, histopatologi
Referensi : The Open Immunology Journal, 2009, 2, 79-85

No. protocol #IM/061

Kapasitasi Fagositosis

Hewan : Rat, Mouse
Modeling : Fagositosis
Metode : PO, IP, parenteral
Analisa : sitologi, imunologi
Referensi : Journal of Cell Science 1992 101: 907-913

No. protocol #IM/062

Splenectomy

Hewan : Rat, Mouse
Modeling : imunosupresi
Metode : Surgery
Analisa : klinis, hematologi, makroskopi, histopatologi
Referensi : Bio Protoc.;
doi: 10.21769/BioProtoc.3317

No. protocol #IM/063

Leukemia

Hewan : Rat, Mouse
Modeling : Cancer
Metode : Induksi
Analisa : klinis, hematologi, makroskopi, histopatologi
Referensi : Cancer Metastasis Rev.; doi: 10.1007/s10555-012-9405-5

No. protocol #IM/064

Keto-acidosis

Hewan : Rat, Mouse
Modeling : pH
Metode : Induksi diet
Analisa : klinis, hematologi, makroskopi, histopatologi
Referensi : AJP, Endocrinokogy and Metabolism; https://doi.org/10.1152/ajpendo.00107.2015

No. protocol #MB/069

Endurance

Hewan : Rat, Mouse
Modeling : –
Metode : Gavage tubing
Analisa : klinis, hematologi, makroskopi, histopatologi
Referensi : Journal of Experimental Biology; doi: 10.1242/jeb.028886

No. protocol #MB/070

Dislipidemia

Hewan : Rat, Mouse
Modeling : –
Metode : Gavage tubing
Analisa : klinis, hematologi, makroskopi, histopatologi
Referensi : Journal of Cardiovascular Pharmacology;
doi: 10.1097/FJC.0000000000000522

No. protocol #MB/071

Uji Efikasi -Organ Sistem Saraf-

Brain ischemia

Hewan : Rat, Mouse
Modeling : Ischemia
Metode : Surgery
Analisa : klinis, makroskopi, histopatologi
Referensi : Front Neurol; doi: 10.3389/fneur.2014.00019

No. protocol #BR/072

Uji Efikasi -Organ Sistem Reproduksi-

Superovulasi

Hewan : Rat, Mouse
Modeling : Superoulasi
Metode : Induksi hormon
Analisa : klinis, makroskopi, histopatologi
Referensi : J Am Assoc Lab Anim Sci.; PMCID: PMC3148645

No. protocol #RP/078

Cystic Ovari

Hewan : Rat, Mouse
Modeling : Histerectomy
Metode : Surgery
Analisa : klinis, makroskopi, histopatologi
Referensi : Reprod Med Biol.; doi: 10.1002/rmb2.12262

No. protocol #RP/079

Cystic Endometrium

Hewan : Rat, Mouse
Modeling : Kista
Metode : Induksi hormon
Analisa : klinis, makroskopi, histopatologi
Referensi : Cancer Med.; doi: 10.1002/cam4.445

No. protocol #RP/080